Francisco Garcia Soriano Selected Research

Hypertonic Saline Solution

1/2013	Hypertonic saline solution drives neutrophil from bystander organ to infectious site in polymicrobial sepsis: a cecal ligation and puncture model.
12/2012	Volume replacement with saline solutions during pancreatitis in rats and the hepatic profiles of apoptotic proteins and heat-shock proteins.
9/2008	Sepsis volume reposition with hypertonic saline solution.
2/2007	Hypertonic saline solution increases the expression of heat shock protein 70 and improves lung inflammation early after reperfusion in a rodent model of controlled hemorrhage.

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Francisco Garcia Soriano Research Topics

Disease

23	Sepsis (Septicemia) 01/2022 - 04/2002
9	Inflammation (Inflammations) 10/2022 - 04/2002
7	Septic Shock (Toxic Shock Syndrome) 01/2022 - 03/2008
6	Endotoxemia 01/2021 - 10/2010
5	Lung Injury 12/2015 - 07/2009
4	Shock 01/2019 - 05/2002
4	Ischemia 02/2016 - 10/2002
3	Reperfusion Injury 02/2016 - 04/2002
3	Critical Illness (Critically Ill) 06/2011 - 03/2006
3	Necrosis 03/2006 - 04/2002
2	Hemorrhage 01/2019 - 02/2007
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 12/2015 - 05/2003
2	Pneumonia (Pneumonitis) 12/2015 - 02/2007
2	Acute Lung Injury 12/2015 - 01/2006
2	Infections 07/2014 - 03/2006
2	Pancreatitis 12/2012 - 07/2009
2	Bacterial Infections (Bacterial Infection) 06/2011 - 01/2009
1	Obesity 10/2022
1	Hepatitis 12/2021
1	Ischemic Stroke 12/2021
1	Neuroinflammatory Diseases 12/2021
1	Multiple Organ Failure (MODS) 12/2021
1	Neoplasms (Cancer) 12/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2021
1	Atherosclerosis 01/2021
1	Pulmonary Emphysema 01/2021
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2019
1	Leptospirosis 01/2019
1	Atrophy 01/2019
1	Edema (Dropsy) 02/2016
1	Pulmonary Edema 02/2016
1	Brain Ischemia (Cerebral Ischemia) 02/2016
1	Heart Failure 01/2016
1	Fibrosis (Cirrhosis) 11/2014
1	Body Weight (Weight, Body) 07/2014
1	Bruton type agammaglobulinemia 05/2013
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 10/2012

Drug/Important Bio-Agent (IBA)

7	CytokinesIBA 10/2022 - 04/2002
6	LipopolysaccharidesIBA 02/2017 - 05/2002
5	Oxidants (Oxidizing Agents)IBA 06/2011 - 04/2002
4	Interleukin-6 (Interleukin 6)IBA 10/2022 - 04/2002
4	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2022 - 04/2002
4	Saline SolutionIBA 02/2017 - 12/2012
4	Hypertonic Saline SolutionIBA 01/2013 - 02/2007
3	olaparibIBA 01/2022 - 01/2019
3	Poly(ADP-ribose) Polymerase InhibitorsIBA 12/2021 - 02/2002
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 04/2002
3	Proteins (Proteins, Gene)FDA Link 02/2017 - 12/2012
3	Interleukin-10 (Interleukin 10)IBA 05/2013 - 04/2002
3	Peroxynitrous Acid (Peroxynitrite)IBA 06/2011 - 05/2002
2	Messenger RNA (mRNA)IBA 10/2022 - 10/2010
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 01/2009
2	Gastrin-Releasing PeptideIBA 10/2012 - 01/2006
2	Tpi(6)-Leu(13)-psi(CH2NH)-Leu(14)- bombesin (6-14)IBA 10/2012 - 01/2006
2	Bombesin Receptors (Bombesin Receptor)IBA 10/2012 - 01/2006
2	Oxygen (Dioxygen)IBA 05/2012 - 09/2010
2	Superoxides (Superoxide)IBA 06/2011 - 09/2010
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 06/2011 - 09/2010
2	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 07/2009 - 02/2007
2	LipidsIBA 01/2008 - 03/2006
2	EmulsionsIBA 01/2008 - 03/2006
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2008 - 03/2006
2	EnzymesIBA 05/2002 - 04/2002
2	N- (oxo- 5,6- dihydrophenanthridin- 2- yl)- N,N- dimethylacetamide hydrochlorideIBA 05/2002 - 02/2002
1	ResistinIBA 10/2022
1	NAD (NADH)IBA 12/2021
1	Pancreatic Elastase (Elastase)IBA 01/2021
1	Lipoproteins (Lipoprotein)IBA 01/2021
1	Cholesterol Ester Transfer ProteinsIBA 01/2021
1	Vitamin D FDA LinkGeneric 01/2020
1	InterleukinsIBA 01/2020
1	Pharmaceutical PreparationsIBA 01/2019
1	Hypertonic SolutionsIBA 01/2019
1	DNA (Deoxyribonucleic Acid)IBA 01/2019
1	AntigensIBA 01/2019
1	Caspase 3 (Caspase-3)IBA 01/2019
1	pristane (pristan)IBA 01/2019
1	Telomerase (Telomerase Reverse Transcriptase)IBA 02/2017
1	CreatineIBA 02/2016
1	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA 01/2016
1	Metalloproteases (Metalloproteinases)IBA 12/2015
1	CollagenIBA 12/2015
1	Cytidine Diphosphate (CDP)IBA 11/2014
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 07/2014
1	salicylhydroxamic acid (SHAM)IBA 07/2014
1	Immunoglobulin M (IgM)IBA 05/2013
1	Agammaglobulinaemia Tyrosine KinaseIBA 05/2013
1	Caspase 2IBA 12/2012
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 12/2012
1	Taurocholic Acid (Sodium Taurocholate)IBA 12/2012
1	Toll-Like Receptors (Toll-Like Receptor)IBA 10/2012
1	Toll-Like Receptor 4IBA 10/2012

Therapy/Procedure

6	Ligation 01/2019 - 04/2002
6	Punctures 01/2019 - 04/2002
5	Therapeutics 12/2021 - 10/2002
3	Resuscitation 12/2015 - 10/2002
2	Investigational Therapies (Experimental Therapy) 01/2022 - 01/2019
1	Artificial Respiration (Mechanical Ventilation) 01/2019
1	Splenectomy 01/2019
1	Nutrition Therapy (Medical Nutrition Therapy) 09/2015